This error surfaced on a customer’s unit that was running Intergraph MPS, IFR and Informer application. The application utilizes an ActiveX control and Windows 7 was prompting the user every time the application was opened.
In the registry, you can add the control ID as a “Safe for Scripting”. Locating the CLSID that the application is listed as is the tough part. In my case, it was fairly simple, because the Intergraph install file included a .reg which listed the ID.
Here is the final .REG I used on Windows 7 Enterprise x64:
More information on setting ActiveX Scripts as “Safe”: http://msdn.microsoft.com/en-us/library/aa751977(v=vs.85).aspx